Pathophysiology is not the sole aspect of hemorrhoids to lack full elucidation. Despite numerous efforts, the true etiopathogenesis of hemorrhoidal disease still remains elusive. Many surgeons have tried to derive conclusions based on operative findings. Many physicians have tried to detect and describe the precise pathophysiological events of symptomatic disease. Hippocrates approached the pathophysiology and the treatment of the disease in his treatise “On Hemorrhoids”.
Primitive references are found in the Old Testament and in Egyptian, Babylonian and Greek written sources. Hemorrhoidal disease has been recorded through centuries of history. If doctors can understand the pathophysiology of hemorrhoidal disease, they will be able to clarify the nature of the associated symptoms and complications and to make the correct therapeutic decision. Returning to basic medical sciences, this mini-review focuses on internal hemorrhoids and aims to define the histology and anatomy of the normal and abnormal internal hemorrhoidal plexus and to encourage clinicians to comprehend the pathophysiology of the disease. Hemorrhoids are classified as internal or external and are viewed as a disease when they become symptomatic. Individual beliefs and historical legends, accompanied by undocumented theories, have established and perpetuated the confusion regarding the mechanisms leading to the development of the disease and the rules governing its treatment. Despite centuries’ of attempts to shed light on its pathophysiology, to cure those affected and to improve sufferers’ quality of life, many aspects of the disease remain elusive. Hemorrhoidal disease is a fairly common and debilitating clinical entity.
0 kommentar(er)
